Thursday, September 24, 2015

The smallest of the URF's (URFA6L), is a 207-nucleotide. The NH-terminal portion of the adenosinetriphosphatase subunit 6 gene has been identified as the animal equivalent of yeast H+-ATPase subunit 8 gene. Functions of the other URFs are still elusive. Immunoprecipitation reactions have proved that URFs 1 through 5 and URF4L encode subunits of a NADH dehydrogenase called complex 1, a complex that has many subunits synthesised in the cytoplasm. The reactions used NADH-ubiquitous oxidoreductase from bovine heart as well as enzyme fractionation studies.

The smallest of the URF's (URFA6L), is a 207-nucleotide. The NH-terminal portion of the adenosinetriphosphatase subunit 6 gene has been identified as the animal equivalent of yeast H+-ATPase subunit 8 gene. Functions of the other URFs are still elusive. Immunoprecipitation reactions have proved that URFs 1 through 5 and URF4L encode subunits of a NADH dehydrogenase called complex 1, a complex that has many subunits synthesised in the cytoplasm. The reactions used NADH-ubiquitous oxidoreductase from bovine heart as well as enzyme fractionation studies.


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The smallest of the URF's gene was found equal to the yeast H+-ATPase subunit 8 gene. However, the functional significance of the others URF's genes were exclusive. 

Re: Revise from Angus Liu

2015年9月24日 下午8:32 於 "angus liu" <angusliuatuic@gmail.com> 寫道:

The smallest of the URF's (URFA6L)has been identified as yeast H+-ATPase subunit 8 gene in animal

.

URF’s (URFA6L) are 207-nucleotide (nt) reading frames

overlapping out of phase the NH2-terminal portion of the adenosinetriphosphatase

(ATPase) subunit 6 gene. The smallest URF’s has been identified as the animal equivalent of the recently

discovered yeast H+-ATPase subunit 8 gene. In contrast, the functional significance of the other URF’s are elusive.    

207-nucleotide (nt) reading frame is the smallest unit of URF's (URFA6L) which
overlaps the NH2-terminal portion of adenosinetriphosphatase
(ATPase) subunit 6 gene. It has been identified as the animal equivalent to recent
discovered yeast H+-ATPase subunit 8 gene. However, function of other URF's is inconclusive.



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